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2004 Guze Symposium Presentation and Poster List

Guze Symposium on Alcoholism: Alcoholism and the Latest Genetics & Neuroscience Findings
February 19, 2004

     Speaker Biographies

     Meeting Awardees

     Presentations*

Alison M. Goate, PhD - Progress Toward Identification of Alcoholism Susceptibility Genes on Chromosome 7 in the COGA dataset

Charles F. Zorumski, MD - Effects of Alcohol and Other Sedatives on the Developing Nervous Nervous System: Implications for Psychiatry

Ting-Kai Li, MD - Genetic & Environmental Influences on Alcohol Drinking Behavior

Kent Hutchison, PhD - Craving Alcohol: Genetic and Pharmacological Factors

Carol A. Prescott, PhD - What Twin Studies Teach Us About the Causes of Alcoholism

Jeanne M. Wehner, PhD - Modeling Behavioral Endophenotypes Related to Alcohol Abuse in Mice 

     Posters*

A.  Smoking and Other Comorbid Traits, Traumatic Events, Treatment

1.     McCutcheon VV, Heath AC, Nelson EC, Bucholz KK, Madden PAF, Martin NG—“Effects of Parental Alcohol Problems, Trauma, and Genetic Effects on Risk for Panic Attacks and Depression.”

2.     Nelson EC—“Traumatic event exposure and alcohol-related outcomes.”

3.     RMEETING AWARDEE:  Nguyen SA, DeLeon CP, Middaugh LD-- “Treating alcohol addiction:  From preclinical to clinical with tiagabine.”

4.     Richardson AE—“Smoking status moderates alcohol hangover frequency.”

5.     Scherrer JF, Xian H, Bucholz KK, Heath AC, Jacob T, True WR—“The role of family and non-family environment in adolescent smoking:  An offspring of twins design.”

6.    Vedeniapin AB, Rohrbaugh JW, Sirevaag EJ, Sher KJ, Heath AC, McGrath M, Sandy R, Ryan C, Goldenberg T, Goebel JA—“The acute effects of alcohol and nicotine on balance.”

7.     Volk H, Scherrer J, Xian H, Bucholz K, Heath A, Jacob T, True W—“A multivariate analysis of Attention Deficit Hyperactivity Disorder and alcohol use in adolescent and young adults.”

B.  Animal Studies of Ethanol

8.    de Erausquin—“Molecular mechanism of neurogenesis suppression by ethanol in adult mice.”

9.    RMEETING AWARDEE:  Fee JR, Sparta DR, Picker MJ, Thiele TE—“Increased ethanol drinking by RIIβ knockout mice:  Assessment of genetic background and testing procedures.”

10.  Indacochea RA, Maas JW, Muglia LM, Vogt SK, Olney JW, Muglia LJ—“Enhanced ethanol neurotoxicity in neonatal adenylyl cyclase knockout mice.”

11.  Maas JW, Izumi Y, Zorumski C, Muglia J—“Enhanced ethanol sensitivity in adenylyl cyclase knockout mice.”

12.  Wozniak DF, Hartman RE, Boyle MP, Vogt SK, Brooks AR, Tenkova T, Young C, Olney J, Muglia LJ—“Apoptotic neurodegeneration induced by ethanol in neonatal mice produces profound learning/memory deficits in juveniles followed by progressive functional recovery in adults.”

13.  Young C, Dikranian K, Labruyer J, Tenkova T, Qin YQ, Olney JW—“Ethanol triggers widespread neuroapoptosis throughout the developing rodent CNS.”

C.  Biology & Neuroscience

14.  RMEETING AWARDEE:  Brunelle C—“Psychostimulant drug users have higher heart rate increases after alcohol intoxication.”

15.  Moulder K, Shute AA, Cormier R, Benz A, Isenberg KE, Zorumski CF, Mennerick S—“Astrocytes modulate activity-dependent survival in a model of developmental apoptosis.”

16.  RMEETING AWARDEE:  Mulholland PJ, Self RL, Harris BR, Little HJ, Littleton JM, Prendergast MA—“Corticosterone modulates ethanol withdrawal-mediated hippocampal damage:  Relation to elevated CA2+ levels.”

17.  Sirevaag EJ—“Cardiovascular responses to combined alcohol and nicotine challenge.”

18.  Striley CLW, Cottler LB—“Men and women vary in physiological dependence to alcohol.”

 D.  Epidemiology, Environmental Impact

19.  Caspers K—“Interaction between biological risk for alcoholism and attachment security in adulthood as predictor of lifetime alcohol use.”

20.  Fox L, Reich W, Beigleiter H, Bierut L, Bucholz K, Constantino J, Hesselbrock V, Kramer J, Kuperman S, Nurnberger J, Petti T, Porjesz B, Schuckit M, Todd R, Reich T—“Early- versus late-adolescence-onset alcoholism:  The impact of externalizing behavior symptoms and parental alcoholism.”

21.  Krishna VAS, Ostella C, Meeks C, Reich W, Ben Abdallah A, Cottler L—“African American mother-daughter drug using patterns.”

22.  Hogan MA—“The persistence of oppositional defiant disorder and the risk for alcohol problems in a community sample of adolescent female twins.”

23.  Moore LM—“The Risk of substance dependence in the siblings of Caucasian and African-American alcohol and cocaine dependent probands.”

24.  Pedersen SL, Thompsen DM, Leuty ME, McCarthy DM—“The influence of obtaining a driver's license on alcohol involvement, parental monitoring, and alcohol availability.”

25.   RMEETING AWARDEE:  Sartor CE, Jacob T—“The role of family environment in the expression of alcoholism among offspring at high genetic risk.”

26.  Spinks R, Caspers K, Langbehn D, Cadoret R—“Examination of school achievement prior to substance abuse onset used to aid in identifying possible heritable factors contributing to low school achievement.”

27.  Thompsen DM, Pedersen SL, Leuty Melanie E, McCarthy DM—“Psychometric validation of a measure of positive drinking and driving outcomes.”

E.  Genetics and Genetic Influences in Humans

28.  Grant JD, Bucholz KK—“Do genetic influences on abuse and dependence overlap?  Explorations using cannabis and alcohol diagnoses.”

29.  Knopik VS, Heath AC, Madden PAF, Bucholz KK, Slutske WS, Nelson EC, Martin NG—“Genetic effects of alcohol dependence: Re-evaluating the importance of psychiatric and other heritable risk factors.”

30.   Langbehn DR, Philibert R, Caspers KM, Cadoret RJ—“Interactions between a 124-bp allele at D2s2944 and alcoholism/sociopathy.”

31.  RMEETING AWARDEE:  Luczak SE, Wall TL, Cook TAR, Shea SH, Carr LG—“ALDH2 status and conduct disorder mediate the relationship between ethnicity and alcohol dependence in Chinese-, Korean-, and White-American college students.”

32.  Pergadia ML, Heath AC, Bucholz KK, Grant JD, Knopik VS, Martin NG, Madden PAF—“Does alcohol dependence mediate genetic influences on DSM-IV nicotine withdrawal?”

33.  Philibert R, Caspers K, Langbehn D, Troughton EP, Yucuis R, Sandhu HK, Cadoret RJ—“Examination of the 124 bp allele in subset of 171 adoptees from Iowa Adoption Studies.”

34.  Price RK, Lobos E, Risk NK, Todd RD –“Association of ALDH2, alcohol sensitivity and sociocultural factors with substance use behavior phenotypes among the Japanese and Vietnamese in the U.S.”

35.  Todorov AA, Bucholz KK, Todd RD, Madden PAF, Nelson EC—“Design of candidate gene studies of drug dependence.”

36.  Waldron M, Heath AC, Turkheimer E, Emery RE, Martin NG—“A genetically-informed study of the association between early alcohol use and teenage pregnancy."

F.  College Drinking

37.  Epler AJ—“Patterns of attendance and drinking in college freshmen in nine social settings:  Relation to alcohol consumption, smoking and drug use.”

38.  Grekin E—“Prevalence and stability of DSM-IV alcohol dependence symptoms during the college years.”

39.  Park A—“The role of drinking motives in change of heavy episodic drinking during the transition to college.”

40.  Rutledge PC—“Patterns of freshman-year alcohol use in the IMPACTS dataset.”

41.  Wood P—“Collegiate alcohol use and its relationship to first year academic performance and attrition.”

G.  MARC-Related

42.   Hudgens RW—“Dr. Guze:  His Career and Achievements.”

43.   “Dr. Theodore Reich:  His Career and Achievements.”

44.   Slutske WS—“MARC Project 4:  Australian children of alcoholic female twins.”

45.   Heath AC—“Midwest Alcoholism Research Center (MARC) Overview.”

* Poster presentations without an active link indicate that we were not given permission to post.  Please direct inquiries to GuzeSymp@matlock.wustl.edu